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Inflammaging: How Chronic Inflammation Ages You Prematurely

May 30, 2025

Hidden inflammation in your body not only leads to premature aging but is at the root of all chronic illness—conditions like heart disease, obesity, diabetes, dementia, depression, cancer, and even autism. Understanding what inflammaging is, its triggers, and how to combat inflammation is a vital component of living healthier and more vibrantly.

The Hidden Damage of Inflammation

Inflammaging refers to chronic, low-grade inflammation that accelerates aging at the cellular level. As we age, the body’s ability to regulate inflammation diminishes, leading to a state of ongoing, low-grade inflammation. This chronic inflammation accelerates the aging process and can resulting in various health complications that can affect our quality of life.

Acute vs. Chronic Inflammation

  • Acute Inflammation: This type of inflammation is a short-term response to injury or infection. Acute inflammation is typically a healthy, protective response that helps the body heal. For example, when you cut your finger, the body sends white blood cells to the area to fight off potential infections, which causes inflammation. This response usually resolves once the injury is healed, and the inflammation subsides.
  • Chronic Inflammation: Unlike acute inflammation, chronic inflammation is a long-term condition that can last for months or years. It occurs when the body’s immune response is continuously activated, often without a clear trigger. Chronic inflammation is often invisible, meaning you may not notice any immediate symptoms, but it can lead to significant health issues over time.

What Triggers Inflammation?

Several factors can trigger chronic inflammation, including:

  1. Poor Diet: A diet high in processed foods, sugar, and unhealthy fats can contribute to inflammation. Foods that promote inflammation include refined carbohydrates, fried foods, and excessive alcohol. 
  2. Unbalanced Gut: A significant connection exists between gut health and inflammation. The gut microbiome plays a critical role in regulating inflammation levels. An imbalanced microbiome, often the result of poor nutrition and lifestyle, can contribute to inflammatory processes.
  3. Estrogen Decline: Estrogen, particularly estradiol, is known for its anti-inflammatory properties, helping to regulate the immune system and reduce inflammation throughout the body. When our estrogen begins to decline during perimenopause this leads to increased production of pro-inflammatory cytokines, signaling molecules that promote inflammation. 
  4. Physical Inactivity: Lack of physical activity is typically linked to excess visceral body fat (the fat which accumulates around the abdomen) which can produce pro-inflammatory cytokines, leading to chronic inflammation in the body.
  5. Stress: Chronic stress leads to hormonal imbalances that can trigger inflammation. High cortisol levels can affect the immune system, making the body more susceptible to inflammatory processes.
  6. Sleep Deprivation: Lack of quality sleep can lead to increased levels of inflammatory markets in the body. Without 7 to 8 hours of sleep a night, cortisol levels increase and cause inflammation in the body potentially leading to lowered defenses in the immune system and an increased risk of developing many chronic conditions. 
  7. Environmental Factors: Exposure to environmental toxins, such as air pollution, chemicals, and heavy metals, chemicals in your skincare products can contribute to chronic inflammation. 

Strategies to Combat Chronic Inflammation

Now that we understand the causes of chronic inflammation, let’s explore some effective strategies to combat it and support our health. 

1. Adopt an Anti-Inflammatory Diet: Emphasizing a diet rich in fruits, vegetables, nuts, whole grains, and healthy fats can help reduce inflammation. Consider incorporating foods known for their anti-inflammatory properties, including:

  • Berries: Rich in antioxidants, berries can help fight inflammation.
  • Fatty Fish: Salmon, mackerel, and sardines are rich in omega-3 fatty acids, which can reduce inflammatory markers
  • Leafy Greens: Spinach, kale, and broccoli are packed with vitamins and minerals that combat inflammation.
  • Turmeric: This spice contains curcumin, a compound known for its anti-inflammatory effects.

2. Work on Your Gut Health: Incorporate probiotics and pre-biotic high fiber foods into your diet. Foods high in prebiotics, such as garlic, onions, and asparagus, feed the good bacteria in the gut. Probiotics, found in fermented foods such as yogurt, kefir, sauerkraut, and kombucha, can help add beneficial bacteria to your body. 

3. Intentional Movement: Regular exercise has an anti-inflammatory effect on the body. Strength training, increasing movement throughout your day (NEAT) and incorporating yoga can help reduce inflammation.

4. Prioritize Sleep: Aim for 7-9 hours of quality sleep each night (harder said than done). This is the time of life where focusing on sleep hygiene practices, such as maintaining a regular sleep schedule and creating a comfortable sleep environment, is important to help with sleep. 

5. Learn to Manage Stress Effectively: We can’t eliminate stress but you can incorporate stress-reducing practices into your daily routine, such as meditation, deep-breathing exercises, or engaging in hobbies you love. Finding time to unwind and relax is crucial in managing chronic inflammation.

6. Stay Hydrated: Drinking plenty of water is vital for maintaining optimal cellular function and flushing out toxins from the body. Aim for at least half your body weight in ounces of water daily.

7. Consult a Health Professional:  If you suspect chronic inflammation is affecting your health, consult a qualified nutrition or health coach. They can help create a personalized wellness plan tailored to your needs.

Take Control of Inflammaging

In my program Live Powerfully, I empower women to understand what is happening inside your body and teach you to nourish yourself with real food and targeted nutrition. If you are ready to reclaim your radiance, click here.

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Hi, I’m Jeannine
Hi, I’m Jeannine

Hi, I’m Jeannine

I'm a certified health and wellness coach with a passion for cooking and photographing beautiful, colorful, healthy food. I provide healthy plant-forward recipe inspiration for those who want to look and feel their healthiest from the inside out. I'm so glad you stopped by!

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6 common mistakes you may be making that’s making healthy eating harder. 

1. Thinking every meal has to be an elaborate recipe. Especially during the week I put together simple assembly line style meals (protein + grain + veggie + sauce) and make a few special recipes on the nights I’ll have more time. Keeping meals simple also were key during the periods I was trying to actively lose weight.

2. Spending hours on meal prep. Meal prep doesn’t have to mean 3 hours on Sunday with the same meals all week. Prep few components throughout on one day (extra protein, grains in the instant pot) and use the ingredients as a base for meals throughout the week. 

3. Shopping for multiple individual recipes. All it takes is a few busy days at work or a sick kid and I have food going to waste in my fridge. Instead I think in components (ground beef, vegetables, grains) and have some go to “assembly line meals” I can adapt. 

4. Not inderstanding portion sizes. I was eating healthy but once I spent time weighing/measuring my food and track it I saw where I was undereating (carbs) and overeating (fats!). I also realized I was eating way too much protein and not enough fiber.

5. Neglecting fiber. just because you eat a lot of vegetables doesn't necessarily mean you're taking in enough fiber. (vegetable salads aren’t a great source, ladies). Being more intentional about fiber with grains, seeds, fruit will help keep you satiated and improve digestion. 

6. Overlooking the freezer. I noe make sure the freezer is always stocked with frozen pre-cut vegetables, rice and proteins. When possible, make extra of soups and sauces to quickly reheat. This ensures you can always pull together a quick healthy meal and avoids defaulting to take out. 

The goal is a system that works in real life. Follow @livepowerfullyco for more ways to get strong, lean, energized and confident in midlife.
•
Follow
6 common mistakes you may be making that’s making healthy eating harder. 1. Thinking every meal has to be an elaborate recipe. Especially during the week I put together simple assembly line style meals (protein + grain + veggie + sauce) and make a few special recipes on the nights I’ll have more time. Keeping meals simple also were key during the periods I was trying to actively lose weight. 2. Spending hours on meal prep. Meal prep doesn’t have to mean 3 hours on Sunday with the same meals all week. Prep few components throughout on one day (extra protein, grains in the instant pot) and use the ingredients as a base for meals throughout the week. 3. Shopping for multiple individual recipes. All it takes is a few busy days at work or a sick kid and I have food going to waste in my fridge. Instead I think in components (ground beef, vegetables, grains) and have some go to “assembly line meals” I can adapt. 4. Not inderstanding portion sizes. I was eating healthy but once I spent time weighing/measuring my food and track it I saw where I was undereating (carbs) and overeating (fats!). I also realized I was eating way too much protein and not enough fiber. 5. Neglecting fiber. just because you eat a lot of vegetables doesn't necessarily mean you're taking in enough fiber. (vegetable salads aren’t a great source, ladies). Being more intentional about fiber with grains, seeds, fruit will help keep you satiated and improve digestion. 6. Overlooking the freezer. I noe make sure the freezer is always stocked with frozen pre-cut vegetables, rice and proteins. When possible, make extra of soups and sauces to quickly reheat. This ensures you can always pull together a quick healthy meal and avoids defaulting to take out. The goal is a system that works in real life. Follow @livepowerfullyco for more ways to get strong, lean, energized and confident in midlife.
5 days ago
View on Instagram |
1/5
The Busy woman’s cheat sheet to changing your body in midlife. Here are six things that I stopped doing that made healthy eating easier and help me get leaner and stronger at 47.

1. Thinking every meal has to be an elaborate recipe. Especially during the week I put together simple assembly line style meals (protein + grain + veggie + sauce) and make a few special recipes on the nights I’ll have more time. 

2. Spending hours on meal prep. Meal prep doesn’t have to mean 3 hours on Sunday with the same meals all week. I prep a few components throughout the day (extra protein, grains in the instant pot) and use ingredients throughout the week. 

3. Planning individual recipes. All it takes is a few busy days at work or a sick kid and I have food going to waste in my fridge. Instead I think in components (ground beef, vegetables, grains) to put something together quickly. 

4. Neglecting portion sizes. I was eating healthy but once I started to weigh my food and track it I saw where I was undereating (carbs) and overeating (fats!). You can be eating clean but macros + calories count too.

5. Neglecting fiber. When I experimented with tracking my food I saw I wasn’t taking in nearly enough fiber (vegetable salads aren’t a great source, ladies). Being more intentional about fiber helped improve my satiety and digestion. 

6. Forgetting about the freezer. I make sure the freezer is always stocked with frozen pre-cut vegetables, rice and proteins. When possible, I  made extra of soups and sauces to quickly reheat. This ensures I can always pull together a quick healthy meal and avoids defaulting to take out. 

The goal is a system that works in real life. Follow @livepowerfullyco for more ways to get strong, lean, energized and confident in midlife
•
Follow
The Busy woman’s cheat sheet to changing your body in midlife. Here are six things that I stopped doing that made healthy eating easier and help me get leaner and stronger at 47. 1. Thinking every meal has to be an elaborate recipe. Especially during the week I put together simple assembly line style meals (protein + grain + veggie + sauce) and make a few special recipes on the nights I’ll have more time. 2. Spending hours on meal prep. Meal prep doesn’t have to mean 3 hours on Sunday with the same meals all week. I prep a few components throughout the day (extra protein, grains in the instant pot) and use ingredients throughout the week. 3. Planning individual recipes. All it takes is a few busy days at work or a sick kid and I have food going to waste in my fridge. Instead I think in components (ground beef, vegetables, grains) to put something together quickly. 4. Neglecting portion sizes. I was eating healthy but once I started to weigh my food and track it I saw where I was undereating (carbs) and overeating (fats!). You can be eating clean but macros + calories count too. 5. Neglecting fiber. When I experimented with tracking my food I saw I wasn’t taking in nearly enough fiber (vegetable salads aren’t a great source, ladies). Being more intentional about fiber helped improve my satiety and digestion. 6. Forgetting about the freezer. I make sure the freezer is always stocked with frozen pre-cut vegetables, rice and proteins. When possible, I made extra of soups and sauces to quickly reheat. This ensures I can always pull together a quick healthy meal and avoids defaulting to take out. The goal is a system that works in real life. Follow @livepowerfullyco for more ways to get strong, lean, energized and confident in midlife
6 days ago
View on Instagram |
2/5
3 breakfasts with 30g+ protein that take less time than scrollng Instagram. Comment MORNING and I'll send it directly to your DMs. 

High-protein, high-fiber, and actually delicious — because healthy shouldn't taste like punishment.

1.  Overnight Chocolate Oats (~35g protein)

2.  Chili-Crisp Scrambled Eggs (~37g protein)

3.  Salmon, Avocado Sandwich (~38g protein)

SAVE this for your next grocery run — and share it with another busy woman who needs it.

#womenover40 #proteinforwomen #workingmom #midlifefitness #perimenopause
3 breakfasts with 30g+ protein that take less time than scrollng Instagram. Comment MORNING and I'll send it directly to your DMs. 

High-protein, high-fiber, and actually delicious — because healthy shouldn't taste like punishment.

1.  Overnight Chocolate Oats (~35g protein)

2.  Chili-Crisp Scrambled Eggs (~37g protein)

3.  Salmon, Avocado Sandwich (~38g protein)

SAVE this for your next grocery run — and share it with another busy woman who needs it.

#womenover40 #proteinforwomen #workingmom #midlifefitness #perimenopause
3 breakfasts with 30g+ protein that take less time than scrollng Instagram. Comment MORNING and I'll send it directly to your DMs. 

High-protein, high-fiber, and actually delicious — because healthy shouldn't taste like punishment.

1.  Overnight Chocolate Oats (~35g protein)

2.  Chili-Crisp Scrambled Eggs (~37g protein)

3.  Salmon, Avocado Sandwich (~38g protein)

SAVE this for your next grocery run — and share it with another busy woman who needs it.

#womenover40 #proteinforwomen #workingmom #midlifefitness #perimenopause
3 breakfasts with 30g+ protein that take less time than scrollng Instagram. Comment MORNING and I'll send it directly to your DMs. 

High-protein, high-fiber, and actually delicious — because healthy shouldn't taste like punishment.

1.  Overnight Chocolate Oats (~35g protein)

2.  Chili-Crisp Scrambled Eggs (~37g protein)

3.  Salmon, Avocado Sandwich (~38g protein)

SAVE this for your next grocery run — and share it with another busy woman who needs it.

#womenover40 #proteinforwomen #workingmom #midlifefitness #perimenopause
3 breakfasts with 30g+ protein that take less time than scrollng Instagram. Comment MORNING and I'll send it directly to your DMs. 

High-protein, high-fiber, and actually delicious — because healthy shouldn't taste like punishment.

1.  Overnight Chocolate Oats (~35g protein)

2.  Chili-Crisp Scrambled Eggs (~37g protein)

3.  Salmon, Avocado Sandwich (~38g protein)

SAVE this for your next grocery run — and share it with another busy woman who needs it.

#womenover40 #proteinforwomen #workingmom #midlifefitness #perimenopause
3 breakfasts with 30g+ protein that take less time than scrollng Instagram. Comment MORNING and I'll send it directly to your DMs. 

High-protein, high-fiber, and actually delicious — because healthy shouldn't taste like punishment.

1.  Overnight Chocolate Oats (~35g protein)

2.  Chili-Crisp Scrambled Eggs (~37g protein)

3.  Salmon, Avocado Sandwich (~38g protein)

SAVE this for your next grocery run — and share it with another busy woman who needs it.

#womenover40 #proteinforwomen #workingmom #midlifefitness #perimenopause
•
Follow
3 breakfasts with 30g+ protein that take less time than scrollng Instagram. Comment MORNING and I'll send it directly to your DMs. High-protein, high-fiber, and actually delicious — because healthy shouldn't taste like punishment. 1.  Overnight Chocolate Oats (~35g protein) 2.  Chili-Crisp Scrambled Eggs (~37g protein) 3.  Salmon, Avocado Sandwich (~38g protein) SAVE this for your next grocery run — and share it with another busy woman who needs it. #womenover40 #proteinforwomen #workingmom #midlifefitness #perimenopause
6 days ago
View on Instagram |
3/5
If you're overwhelmed by all the health advice for women over 40, comment HABITS and you can immediately download the Health Edit - with simple habits you can start today for immediate return, questions to bring to your doctor, and labs worth discussing.

Here's something I wish more women understood:
Not every healthy habit deserves the same amount of your time and energy.

Three intentional strength workouts may do more for your goals than five random classes. 

Eating enough to support your activity may serve you better than cutting another 200 calories. 

And an extra hour of sleep might be more valuable than another early morning workout.

The point isn't to do everything. It's to understand what your body needs now and focus your effort there.

That's the philosophy behind Live Powerfully. I help ambitious women in midlife cut through the wellness noise and build personalized strategies for strength, energy, and long-term health—without making wellness another full-time job.

Comment HABITS and let's get you started.

Follow @LivePowerfullyCo for less wellness noise and more of what actually works.

#perimenopause #womenover40 #womenshealth #workingmom #workingmomlife
•
Follow
If you're overwhelmed by all the health advice for women over 40, comment HABITS and you can immediately download the Health Edit - with simple habits you can start today for immediate return, questions to bring to your doctor, and labs worth discussing. Here's something I wish more women understood: Not every healthy habit deserves the same amount of your time and energy. Three intentional strength workouts may do more for your goals than five random classes. Eating enough to support your activity may serve you better than cutting another 200 calories. And an extra hour of sleep might be more valuable than another early morning workout. The point isn't to do everything. It's to understand what your body needs now and focus your effort there. That's the philosophy behind Live Powerfully. I help ambitious women in midlife cut through the wellness noise and build personalized strategies for strength, energy, and long-term health—without making wellness another full-time job. Comment HABITS and let's get you started. Follow @LivePowerfullyCo for less wellness noise and more of what actually works. #perimenopause #womenover40 #womenshealth #workingmom #workingmomlife
7 days ago
View on Instagram |
4/5
This is where I think so many high-achieving women in midlife get stuck....

We're used to believing that more effort + less calories equals better results. So when our bodies don't respond to that strategy anymore, we double down.

But here's what I wish I'd understood sooner: if your whole goal is just to burn calories, you aren't building anything that is gonna support your metabolism in a long-term.

If you want to build muscle, you need a plan that challenges your muscles progressively (Ps - that doesn't always mean lifting heavier weights, but we'll get to that in another post.) 

You need enough food to support that work. 

And you need recovery so your body can actually adapt.

It's not about abandoning cardio or never being in a calorie deficit. It's about understanding how all the pieces work together instead of treating each workout like a transaction for calories in and out.

**This is exactly what I help women do through Live Powerfully.**

We look at your nutrition, strength training, recovery, and the realities of your schedule to build a personalized health strategy that supports your goals without making wellness another full-time job.

Because you've already built a big life. Your health strategy should help you live it.

Follow @LivePowerfullyCo for less wellness noise and more of what actually works.

**Want to explore 1:1 support?** DM me POWER then we can set up a 1:1 exploratory call.
•
Follow
This is where I think so many high-achieving women in midlife get stuck.... We're used to believing that more effort + less calories equals better results. So when our bodies don't respond to that strategy anymore, we double down. But here's what I wish I'd understood sooner: if your whole goal is just to burn calories, you aren't building anything that is gonna support your metabolism in a long-term. If you want to build muscle, you need a plan that challenges your muscles progressively (Ps - that doesn't always mean lifting heavier weights, but we'll get to that in another post.) You need enough food to support that work. And you need recovery so your body can actually adapt. It's not about abandoning cardio or never being in a calorie deficit. It's about understanding how all the pieces work together instead of treating each workout like a transaction for calories in and out. **This is exactly what I help women do through Live Powerfully.** We look at your nutrition, strength training, recovery, and the realities of your schedule to build a personalized health strategy that supports your goals without making wellness another full-time job. Because you've already built a big life. Your health strategy should help you live it. Follow @LivePowerfullyCo for less wellness noise and more of what actually works. **Want to explore 1:1 support?** DM me POWER then we can set up a 1:1 exploratory call.
2 weeks ago
View on Instagram |
5/5
@eatbeautifullyblog

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